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Year

Day

2024
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October 17, 2024
Original Investigation

Buprenorphine/Naloxone vs Methadone for the Treatment of Opioid Use Disorder

Bohdan Nosyk, PhD; Jeong Eun Min, MSc; Fahmida Homayra, MSc; et al.
Abstract Full Text
JAMA. Published online October 17, 2024. doi:10.1001/jama.2024.16954

This population-based retrospective cohort study uses linked health administrative databases to assess the risk of treatment discontinuation and mortality among adults in British Columbia, Canada, receiving buprenorphine/naloxone vs methadone for the treatment of opioid use disorder.

Research Letter

Effect of Electric Fans on Body Core Temperature in Older Adults Exposed to Extreme Indoor Heat

Fergus K. O’Connor, PhD; Robert D. Meade, PhD, MPH; Katie E. Wagar, BHKRC; et al.
Abstract Full Text
JAMA. Published online October 17, 2024. doi:10.1001/jama.2024.19457

This study assessed whether electric fans limit core temperature increases in adults aged 65 to 85 years exposed to conditions similar to those experienced in homes during heat waves in North America.

Viewpoint

Health and the 2024 US Election

Methadone’s Moment

Michael A. Incze, MD, MSEd; Caty Simon; Leslie W. Suen, MD, MAS
Abstract Full Text
JAMA. Published online October 17, 2024. doi:10.1001/jama.2024.19914

This work discusses unfettering methadone from outdated regulations to empower patients to access treatment and advocate for methadone's expansion in their local communities by working with pharmacies and local health systems.

A Piece of My Mind

When One Day Becomes Today

Joseph A. Pettus, MD
Abstract Full Text
JAMA. Published online October 17, 2024. doi:10.1001/jama.2024.19091

After he learned that his congenital bicuspid aortic valve needed replacement, a urologic oncologist describes, in this narrative medicine essay, the pain and helplessness he felt while recovering from surgery.

JAMA Revisited

Aging and Chronic Illness

Abstract Full Text
JAMA. Published online October 17, 2024. doi:10.1001/jama.2023.18452
Comment & Response

Review of Chronic Pruritus

Chaker Ben Salem, MD; Nadia Ghariani, MD
Abstract Full Text
JAMA. Published online October 17, 2024. doi:10.1001/jama.2024.17978

Review of Chronic Pruritus—Reply

Gil Yosipovitch, MD; Daniel Butler, MD
Abstract Full Text
JAMA. Published online October 17, 2024. doi:10.1001/jama.2024.17981
October 16, 2024
Research Letter

Breast Cancer in Users of Levonorgestrel-Releasing Intrauterine Systems

Lina Steinrud Mørch, MSc, PhD; Amani Meaidi, MD, PhD; Giulia Corn, MSc, PhD; et al.
Abstract Full Text
JAMA. Published online October 16, 2024. doi:10.1001/jama.2024.18575

This study uses data from nationwide Danish registries to assesses breast cancer risk with continuous use of levonorgestrel-releasing intrauterine systems, accounting for other hormonal exposures.

Viewpoint

AI in Medicine

FTC Regulation of AI-Generated Medical Disinformation

Claudia E. Haupt, PhD, JSD; Mason Marks, MD, JD
Abstract Full Text
JAMA. Published online October 16, 2024. doi:10.1001/jama.2024.19971

This Viewpoint discusses the need to address all forms of AI-generated medical disinformation, regardless of whether it involves impersonating real or fictional professionals, medical societies, or research institutions, and the part that the Federal Trade Commission can play in achieving that goal.

Health and the 2024 US Election

Helping Dual-Eligible Individuals Navigate Medicare and Medicaid

Kenton J. Johnston, PhD; Eric T. Roberts, PhD; Jose F. Figueroa, MD, MPH
Abstract Full Text
JAMA. Published online October 16, 2024. doi:10.1001/jama.2024.20355

This Viewpoint discusses helping dual-eligible beneficiaries navigate Medicare and Medicaid coverage options.

JAMA Insights

Antibiotics for Pediatric Acute Bacterial Sinusitis

Kathleen Chiotos, MD, MSCE; Jeffrey S. Gerber, MD, PhD
Abstract Full Text
has active quiz
JAMA. Published online October 16, 2024. doi:10.1001/jama.2024.2018

This JAMA Insights examines antibiotic selection for the treatment of acute bacterial rhinosinusitis in US pediatric patients, specifically amoxicillin vs amoxicillin-clavulanate.

Editor's Note

Poetry, Again, Confronts Death

Rafael Campo, MD, MA
Abstract Full Text
JAMA. Published online October 16, 2024. doi:10.1001/jama.2024.14742
Poetry and Medicine

Again

Kathleen Brodowski, MD
Abstract Full Text
JAMA. Published online October 16, 2024. doi:10.1001/jama.2024.14573
October 15, 2024
Original Investigation

AI in Medicine

Testing and Evaluation of Health Care Applications of Large Language Models: A Systematic Review

Suhana Bedi, BA; Yutong Liu, MA; Lucy Orr-Ewing, BA; et al.
Abstract Full Text
free access
JAMA. Published online October 15, 2024. doi:10.1001/jama.2024.21700

This systematic review characterizes the current performance of large language models in evaluating clinical health care settings, including uniformity, thoroughness, and robustness and proposes a framework for their testing and evaluation across health care applications.

Research Letter

HLA-DRB1*01:03 and Severe Ulcerative Colitis

Marie Vibeke Vestergaard, MSc; Anne Krogh Nøhr, PhD; Kristine Højgaard Allin, MD, PhD; et al.
Abstract Full Text
free access
JAMA. Published online October 15, 2024. doi:10.1001/jama.2024.20429

This Danish nationwide genome-wide association study aims to identify biomarkers of severe vs less severe ulcerative colitis.

Special Communication

AI in Medicine

FDA Perspective on the Regulation of Artificial Intelligence in Health Care and Biomedicine

Haider J. Warraich, MD; Troy Tazbaz, BS; Robert M. Califf, MD
Abstract Full Text
free access has active quiz
JAMA. Published online October 15, 2024. doi:10.1001/jama.2024.21451

This Special Communication examines advances in the use of artificial intelligence in health care and biomedicine and how regulatory entities like the US Food and Drug Administration must evaluate how artificial intelligence operates within these sectors to develop appropriate regulatory frameworks.

Viewpoint

AI in Medicine

Translating AI for the Clinician

Manesh R. Patel, MD; Suresh Balu, MS, MBA; Michael J. Pencina, PhD
Abstract Full Text
free access
JAMA. Published online October 15, 2024. doi:10.1001/jama.2024.21772

This Viewpoint explores how artificial intelligence technologies can adopt a clinical practice framework to identify use cases and outline the technology’s objectives and potential uses in modern health care.

October 14, 2024
Research Letter

Health and the 2024 US Election

Information About Sexual and Gender Minority Services and Policies on US Hospital Websites

Sahil Sandhu, MSc; Michael Liu, MPhil; King Fok, MD, MSc; et al.
Abstract Full Text
JAMA. Published online October 14, 2024. doi:10.1001/jama.2024.18345

This cross-sectional study assesses the extent to which hospitals provide information related to sexual and gender minority policies and health services on their websites.

Trends in Oral and Injectable HIV Preexposure Prophylaxis Prescriptions in the US, 2013-2023

Laura M. Mann, PhD, MPH; Weiming Zhu, MD, PhD; Ya-Lin A. Huang, PhD; et al.
Abstract Full Text
JAMA. Published online October 14, 2024. doi:10.1001/jama.2024.21493

This study examines the prescribing trends of 3 oral preexposure prophylaxis medications and a long-acting injectable option from 2013 to 2023.

Review

Mpox Clinical Presentation, Diagnostic Approaches, and Treatment Strategies: A Review

Boghuma K. Titanji, MD; Aniruddha Hazra, MD; Jason Zucker, MD, MS
Abstract Full Text
free access has active quiz
JAMA. Published online October 14, 2024. doi:10.1001/jama.2024.21091

This review examines the epidemiology, transmission, clinical presentation, assessment and diagnosis, prognosis, management and treatment, and prevention of mpox.

JAMA Insights

Preexposure Prophylaxis (PrEP) for HIV

Matthew A. Spinelli, MD; Kenneth Ngure, MPH, PhD; Monica Gandhi, MD, MPH
Abstract Full Text
has active quiz has audio
JAMA. Published online October 14, 2024. doi:10.1001/jama.2024.16984

This JAMA Insights discusses the expanding PrEP options for preventing HIV, including the considerations for initiation and follow-up and implementation challenges of these medications.

  • Podcast: Preexposure Prophylaxis (PrEP) Options for HIV
JAMA Patient Page

What Is Doxycycline Postexposure Prophylaxis?

Danica Rockney, MD; Preeti Malani, MD, MSJ
Abstract Full Text
free access has audio
JAMA. Published online October 14, 2024. doi:10.1001/jama.2024.18016

This JAMA Patient Page describes doxycycline postexposure prophylaxis (doxyPEP), a medication prescribed to prevent certain sexually transmitted bacterial infections in people at increased risk.

  • Podcast: Preexposure Prophylaxis (PrEP) Options for HIV
Comment & Response

Approach to Hospital Preparedness for Acute Surge Events Due to Emerging Infectious Diseases

George L. Anesi, MD, MSCE
Abstract Full Text
JAMA. Published online October 14, 2024. doi:10.1001/jama.2024.17700

Approach to Hospital Preparedness for Acute Surge Events Due to Emerging Infectious Diseases—Reply

Rahi Abouk, PhD; David Powell, PhD
Abstract Full Text
JAMA. Published online October 14, 2024. doi:10.1001/jama.2024.17703
October 11, 2024
This Week in JAMA

Audio Highlights: October 5-11, 2024

Abstract Full Text
free access has audio
JAMA. Published online October 11, 2024. doi:10.1001/jama.2023.18423
  • Podcast: Transfusion Thresholds in Acute Brain Injury, Electronic Flu Vaccine Nudges, a New OTC Daily Contraceptive, and more
Original Investigation

Electronic Nudges to Increase Influenza Vaccination in Patients With Chronic Diseases: A Randomized Clinical Trial

Niklas Dyrby Johansen, MD, PhD; Muthiah Vaduganathan, MD, MPH; Ankeet S. Bhatt, MD, MBA, ScM; et al.
Abstract Full Text
JAMA. Published online October 11, 2024. doi:10.1001/jama.2024.21060

This randomized clinical trial evaluates whether behaviorally informed electronically delivered letter-based nudges could increase influenza vaccination among adults with chronic diseases.

Medical News & Perspectives

Quick Uptakes

Bird Flu Is Primarily Transmitted Among Dairy Cattle Through Milking, Study Suggests

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 11, 2024. doi:10.1001/jama.2024.21042

This Medical News article discusses a recent study of H5N1 avian influenza transmission in dairy cows.

Medical News in Brief

Weekly Insulin May Be as Effective as Once Daily for Type 2 Diabetes

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 11, 2024. doi:10.1001/jama.2024.20116

More Than Half of US Adults With Uncontrolled Hypertension Don’t Know They Have It

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 11, 2024. doi:10.1001/jama.2024.20117

Review: Treatment Options for GSM Have “Modest” Effect on Symptoms

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 11, 2024. doi:10.1001/jama.2024.20118

Opt-Out Syphilis Screening in EDs Could Substantially Expand Case Detection

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 11, 2024. doi:10.1001/jama.2024.20119

Study: Single Dose of Modified Smallpox Vaccine Effective for Mpox

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 11, 2024. doi:10.1001/jama.2024.20120

WHO: Cholera Cases Increased in 2023

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 11, 2024. doi:10.1001/jama.2024.20121

Fewer US Students Vaping, but Nicotine Pouch Use Stays Flat

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 11, 2024. doi:10.1001/jama.2024.20122

Recalled Cardiovascular Devices Rarely Undergo Sufficient Testing

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 11, 2024. doi:10.1001/jama.2024.20123
October 10, 2024
Research Letter

Payments by Drug and Medical Device Manufacturers to US Peer Reviewers of Major Medical Journals

David-Dan Nguyen, MDCM, MPH; Anju Muramaya; Anna-Lisa Nguyen, BHSc; et al.
Abstract Full Text
JAMA. Published online October 10, 2024. doi:10.1001/jama.2024.17681

This study characterizes payments by drug and medical device manufacturers to US peer reviewers of major medical journals.

Viewpoint

AI in Medicine

Disability Rights to Accessible Virtual Health Care

Jessica L. Roberts, JD
Abstract Full Text
JAMA. Published online October 10, 2024. doi:10.1001/jama.2024.16528

This Viewpoint discusses the new federal regulations that require health care institutions to develop virtual care technologies that are accessible to patients with disabilities.

A Piece of My Mind

So Visibly a Mother

Emily Pinto Taylor, MD
Abstract Full Text
JAMA. Published online October 10, 2024. doi:10.1001/jama.2024.17993

In this narrative medicine essay, an internal medicine physician reflects on her intentional and visible efforts to model for young physicians the balance between career and parenthood.

JAMA Revisited

Role of the Pathologist in Diagnosis

Abstract Full Text
JAMA. Published online October 10, 2024. doi:10.1001/jama.2023.18445
JAMA Patient Page

Cannabinoid Hyperemesis Syndrome

Maria Isabel Angulo, MD
Abstract Full Text
free access
JAMA. Published online October 10, 2024. doi:10.1001/jama.2024.9716

This JAMA Patient Page describes cannabinoid hyperemesis syndrome, a gastrointestinal condition associated with frequent and long-term use of cannabis.

October 9, 2024
Original Investigation

Caring for the Critically Ill Patient

Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury: The TRAIN Randomized Clinical Trial

Fabio Silvio Taccone, MD, PhD; Carla Rynkowski Bittencourt, MD, PhD; Kirsten Møller, MD, PhD; et al.
Abstract Full Text
has active quiz has audio
JAMA. Published online October 9, 2024. doi:10.1001/jama.2024.20424

This randomized clinical trial assesses the effect of a liberal vs a restrictive hemoglobin threshold for red blood cell transfusion on unfavorable neurological outcome in patients with acute brain injury.

  • Podcast: JAMA Critical Care Research at ESICM Congress 2024

Caring for the Critically Ill Patient

Effect of Tele-ICU on Clinical Outcomes of Critically Ill Patients: The TELESCOPE Randomized Clinical Trial

Adriano J. Pereira, MD, PhD; Danilo T. Noritomi, MD, PhD; Maura Cristina dos Santos, RN; et al.
Abstract Full Text
has audio
JAMA. Published online October 9, 2024. doi:10.1001/jama.2024.20651

This parallel cluster randomized clinical trial examines the effect of daily multidisciplinary rounds conducted via telemedicine by a board-certified intensivist on length of stay in the intensive care unit in critically ill adult patients in Brazil.

  • Podcast: JAMA Critical Care Research at ESICM Congress 2024

Caring for the Critically Ill Patient

Extracorporeal Blood Purification and Acute Kidney Injury in Cardiac Surgery: The SIRAKI02 Randomized Clinical Trial

Xosé Pérez-Fernández, PhD; Arnau Ulsamer, PhD; María Cámara-Rosell, PhD; et al.
Abstract Full Text
has audio
JAMA. Published online October 9, 2024. doi:10.1001/jama.2024.20630

This randomized clinical trial examines whether the use of an extracorporeal blood purification device in a nonemergent cardiac surgery population reduces cardiac surgery associated–acute kidney injury after cardiopulmonary bypass.

  • Podcast: JAMA Critical Care Research at ESICM Congress 2024

Caring for the Critically Ill Patient

Frequency of Screening and Spontaneous Breathing Trial Techniques: A Randomized Clinical Trial

Karen E. A. Burns, MD, MSc; Jessica Wong, MD, MPH; Leena Rizvi, BSc; et al.
Abstract Full Text
has audio
JAMA. Published online October 9, 2024. doi:10.1001/jama.2024.20631

This randomized clinical trial compares the effects of screening frequency (once-daily vs more frequent screening) and spontaneous breathing trial techniques (pressure-supported vs T-piece spontaneous breathing trial) on the time to successful extubation among critically ill adults who required invasive mechanical ventilation.

  • Podcast: JAMA Critical Care Research at ESICM Congress 2024
Editorial

Shifting Balance of the Risk-Benefit of Restrictive Transfusion Strategies in Neurocritically Ill Patients—Is Less Still More?

Alexis F. Turgeon, MD, MSc; François Lauzier, MD, MSc
Abstract Full Text
has audio
JAMA. Published online October 9, 2024. doi:10.1001/jama.2024.20416
  • Podcast: JAMA Critical Care Research at ESICM Congress 2024

Evaluating Complex Technological Innovations in Critical Care—Current Challenges and Future Directions

Kelly C. Vranas, MD, MCR; Jeremy M. Kahn, MD, MS
Abstract Full Text
has audio
JAMA. Published online October 9, 2024. doi:10.1001/jama.2024.19854
  • Podcast: JAMA Critical Care Research at ESICM Congress 2024

Impact of Adsorptive Blood Purification on Kidney Outcomes

Yuenting Diana Kwong, MD, MAS; Kathleen D. Liu, MD, PhD, MAS
Abstract Full Text
has audio
JAMA. Published online October 9, 2024. doi:10.1001/jama.2024.20928
  • Podcast: JAMA Critical Care Research at ESICM Congress 2024

Ventilator Weaning Strategies—Managing Interaction Between Randomized Treatments

Steven A. Webb, MPH, PhD; Lindsay R. Berry, PhD; Ary Serpa Neto, MD, MSc, PhD
Abstract Full Text
has audio
JAMA. Published online October 9, 2024. doi:10.1001/jama.2024.19853
  • Podcast: JAMA Critical Care Research at ESICM Congress 2024
JAMA Insights

Women's Health

Over-the-Counter Oral Contraceptives

Daniel Grossman, MD; Elizabeth T. Kinsey, MD
Abstract Full Text
has active quiz has audio
JAMA. Published online October 9, 2024. doi:10.1001/jama.2024.16474

This JAMA Insights discusses the first over-the-counter progestin-only oral contraceptive available in the US, including its effectiveness, mechanism of action, and accessibility.

  • Podcast: Update on Over-the-Counter (OTC) Contraception
Poetry and Medicine

Glorified

Donna Pucciani
Abstract Full Text
JAMA. Published online October 9, 2024. doi:10.1001/jama.2024.13678
Comment & Response

Lifestyle Interventions for Obesity

Catherine L. Davis, PhD; Kate Lorig, DrPH
Abstract Full Text
JAMA. Published online October 9, 2024. doi:10.1001/jama.2024.17533

Lifestyle Interventions for Obesity—Reply

Jamy D. Ard, MD; Kristina H. Lewis, MD; Justin B. Moore, PhD
Abstract Full Text
JAMA. Published online October 9, 2024. doi:10.1001/jama.2024.17536
October 8, 2024
Editorial

AI in Medicine

Hello, World—Introducing JAMA+ AI

Roy H. Perlis, MD, MSc; Kirsten Bibbins-Domingo, PhD, MD, MAS
Abstract Full Text
free access has multimedia has audio
JAMA. Published online October 8, 2024. doi:10.1001/jama.2024.21559
  • Video: Five Big Ideas in AI and Health With JAMA+ AI Editor in Chief Roy Perlis
  • Podcast: What Lessons Does the VA’s Experience Building Electronic Health Records Hold for AI?
Medical News & Perspectives

AI in Medicine

The VA Was an Early Adopter of Artificial Intelligence to Improve Care—Here’s What They Learned

Roy Perlis, MD, MSc
Abstract Full Text
free access has audio
JAMA. Published online October 8, 2024. doi:10.1001/jama.2024.20563

This Medical News story is an interview about the US Department of Veterans Affairs’ pioneering work in using artificial intelligence to improve patient care.

  • Podcast: What Lessons Does the VA’s Experience Building Electronic Health Records Hold for AI?
October 7, 2024
Research Letter

Testing of New Drugs Approved From 2015 Through 2021 Under the US Pediatric Research Equity Act

Ian T. T. Liu, MD, JD, MPH, MS; Thomas J. Hwang, MD; Aaron S. Kesselheim, MD, JD, MPH
Abstract Full Text
JAMA. Published online October 7, 2024. doi:10.1001/jama.2024.18338

This study uses public US Food and Drug Administration lists to identify new drugs approved from 2015 through 2021 to examine recent estimates of compliance with and timing of pediatric testing requirements after passage of the Pediatric Research Equity Act.

Viewpoint

COVID-19 Therapeutics for Nonhospitalized Older Adults

Pragna Patel, MD, MPH; David E. Wentworth, PhD; Demetre Daskalakis, MD
Abstract Full Text
JAMA. Published online October 7, 2024. doi:10.1001/jama.2024.16460

This Viewpoint summarizes the factors contributing to increased risk of severe outcomes and hospitalization associated with COVID-19 among older adults, stresses the importance of assessing COVID-19 risk before infection occurs, calls for all immunocompromised older adults to be considered for COVID-19 treatment, and details 3 recommended COVID-19 therapies.

Comment & Response

Evaluating Tools for Assessing Bias in a Meta-Analysis of Clinical Trials on Race and RAS Blockade

Jianguo Xu, MMS; Ya Gao, PhD; Jinhui Tian, PhD
Abstract Full Text
JAMA. Published online October 7, 2024. doi:10.1001/jama.2024.17525

Evaluating Tools for Assessing Bias in a Meta-Analysis of Clinical Trials on Race and RAS Blockade—Reply

Li Shen, MBChB, PhD; Pardeep S. Jhund, MBChB, MSc, PhD; John J. V. McMurray, MD
Abstract Full Text
JAMA. Published online October 7, 2024. doi:10.1001/jama.2024.17530
October 4, 2024
This Week in JAMA

Audio Highlights: September 30-October 4, 2024

Abstract Full Text
free access has audio
JAMA. Published online October 4, 2024. doi:10.1001/jama.2023.18416
  • Podcast: H pylori Screening for Gastric Cancer Prevention, Antitachycardia Pacing in Patients with ICD, Dialysis Review, and more
Medical News & Perspectives

Semaglutide Updates, Hypertension Triple Pills, and More—Heart Health Highlights From ESC Congress

Jennifer Abbasi
Abstract Full Text
free access has audio
JAMA. Published online October 4, 2024. doi:10.1001/jama.2024.19544

This Medical News article is an interview with European Society of Cardiology Vice President Carlos Aguiar, MD, about clinical research highlights from the largest scientific meeting in cardiovascular medicine, held recently in London.

  • Podcast: Heart Health Highlights From ESC Congress

Could the Body Roundness Index One Day Replace the BMI?

Kate Schweitzer
Abstract Full Text
free access
JAMA. Published online October 4, 2024. doi:10.1001/jama.2024.20115

This Medical News article discusses a newer measure for assessing health risks associated with fat than the body mass index, and the likelihood of it being adopted in clinical settings.

Medical News in Brief

NIH: Adults Still Using Marijuana and Psychedelics at Record Levels

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 4, 2024. doi:10.1001/jama.2024.19688

Study: Starting Second-Trimester Abortions at Home Safely Reduces Hospital Time

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 4, 2024. doi:10.1001/jama.2024.19689

High Drug Costs Influence Nonadherence to Medications Among Older Adults

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 4, 2024. doi:10.1001/jama.2024.19690

FDA Issues Rules Restricting the Sale of Tobacco to Those 21 Years or Older

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online October 4, 2024. doi:10.1001/jama.2024.19691
October 3, 2024
Original Investigation

Assessment of Antitachycardia Pacing in Primary Prevention Patients: The APPRAISE ATP Randomized Clinical Trial

Claudio Schuger, MD; Boyoung Joung, MD, PhD; Kenji Ando, MD; et al.
Abstract Full Text
JAMA. Published online October 3, 2024. doi:10.1001/jama.2024.16531

This randomized clinical trial assesses the role of antitachycardia pacing in terminating fast ventricular tachycardia in primary prevention patients with implantable cardioverter-defibrillators with contemporary programming.

Research Letter

Decline of Mpox Antibody Responses After Modified Vaccinia Ankara–Bavarian Nordic Vaccination

Ai-ris Y. Collier, MD; Katherine McMahan, MS; Catherine Jacob-Dolan, PhD; et al.
Abstract Full Text
free access
JAMA. Published online October 3, 2024. doi:10.1001/jama.2024.20951

This study assesses mpox-specific immune responses for 12 months after MVA-BN vaccination.

Viewpoint

Environmental Determinants of Health—Time to Redefine the Social History?

Peter M. Rabinowitz, MD, MPH; Michele Barry, MD
Abstract Full Text
JAMA. Published online October 3, 2024. doi:10.1001/jama.2024.19490

This Viewpoint discusses how increasing climate change and other environmental hazards contribute to greater adverse health effects, particularly for socially vulnerable populations, and calls for improved gathering of social and environmental history data and risk assessment in routine patient encounters.

Crossing the Equity Chasm: Addressing a Second Valley of Death in Biomedical Innovation

Victor J. Dzau, MD; Emily L. Shambaugh, MPH; Melissa H. Laitner, PhD, MPH
Abstract Full Text
JAMA. Published online October 3, 2024. doi:10.1001/jama.2024.20677

This Viewpoint discusses how medical innovation often does not reach vulnerable populations, a lack that results in disparities in morbidity and mortality globally.

A Piece of My Mind

Amid the Wait

Cia Merin Bishop, MD
Abstract Full Text
JAMA. Published online October 3, 2024. doi:10.1001/jama.2024.17479

In this narrative medicine essay, a pediatric palliative care physician undergoing in vitro fertilization extends her compassionate solidarity to female physicians who, like her, are anxious to start their families.

Editorial

Shock First or Pace First to Break Ventricular Tachycardia?A New Layer of Complexity in ICD Shared Decision-Making

Amneet Sandhu, MD, MSc; Daniel Matlock, MD, MPH; Paul D. Varosy, MD
Abstract Full Text
JAMA. Published online October 3, 2024. doi:10.1001/jama.2024.19416
JAMA Clinical Challenge

A 9-Year-Old Child With a Large Thoracic Mass

Chenghao Chen, MD, PhD; Jie Yu, MD, PhD; Qi Zeng, MD
Abstract Full Text
has active quiz
JAMA. Published online October 3, 2024. doi:10.1001/jama.2024.16482

A healthy 9-year-old had 10 days of nonproductive cough without fever, wheeze, chest pain, or abdominal pain but with diminished breath sounds in the right lower lung field. Results of laboratory testing were unremarkable; computed tomography revealed a fat-density mass in the right anterior mediastinum. What is the diagnosis and what would you do next?

JAMA Patient Page

What Are Uterine Fibroids?

Rebecca Voelker, MSJ
Abstract Full Text
free access
JAMA. Published online October 3, 2024. doi:10.1001/jama.2024.12984

This JAMA Patient Page describes uterine fibroids, their signs and symptoms, diagnosis procedures, and treatment options.

October 2, 2024
Research Letter

Spending by the Veterans Health Administration for Medicare Advantage Dual Enrollees, 2011-2020

David J. Meyers, PhD; Aaron L. Schwartz, MD, PhD; Lan Jiang, MS; et al.
Abstract Full Text
JAMA. Published online October 2, 2024. doi:10.1001/jama.2024.18073

This study assesses veterans’ dual enrollment in the Veterans Health Administration (VHA) and Medicare Advantage and VHA spending from 2011 through 2020.

Viewpoint

Integrating Clinical Trials and Practice

Making Pragmatic Clinical Trials More Pragmatic

Richard Platt, MD, MSc; Hayden B. Bosworth, PhD; Gregory E. Simon, MD
Abstract Full Text
JAMA. Published online October 2, 2024. doi:10.1001/jama.2024.19528

This Viewpoint discusses pragmatic trials and their role in developing new knowledge that can be broadly applicable throughout the health care system.

Rare Disease Innovation at the FDA—Opportunities for Implementation

Carolyn K. Shore, PhD; Tequam L. Worku, MPH; Jeffrey Kahn, PhD, MPH
Abstract Full Text
JAMA. Published online October 2, 2024. doi:10.1001/jama.2024.20358

This Viewpoint discusses new pathways for researchers to seek collaboration when conducting studies on treatments for rare diseases and conditions.

Review

Dialysis for Chronic Kidney Failure: A Review

Jennifer E. Flythe, MD, MPH; Suzanne Watnick, MD
Abstract Full Text
has active quiz has audio
JAMA. Published online October 2, 2024. doi:10.1001/jama.2024.16338

This narrative review explores the use of maintenance hemodialysis and peritoneal dialysis in the treatment of dialysis-dependent chronic kidney failure, including diagnosis, pathophysiology, and disease management.

  • Podcast: Dialysis for Chronic Kidney Failure
Correction

Incorrect Department Name

Abstract Full Text
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JAMA. Published online October 2, 2024. doi:10.1001/jama.2023.14247

Error in Byline

Abstract Full Text
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JAMA. Published online October 2, 2024. doi:10.1001/jama.2024.11331

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