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October 14, 2024
Viewpoint

Collaborative Dementia Care During the New Therapeutic Era

Abstract Full Text
JAMA Neurol. Published online October 14, 2024. doi:10.1001/jamaneurol.2024.3379

This Viewpoint advocates for the implementation of collaborative care with care navigation in the diagnosis and treatment of Alzheimer disease.

Original Investigation

Multisite Skin Biopsies vs Cerebrospinal Fluid for Prion Seeding Activity in the Diagnosis of Prion Diseases

Abstract Full Text
JAMA Neurol. Published online October 14, 2024. doi:10.1001/jamaneurol.2024.3458

This diagnostic study evaluates the ability of multiple skin biopsies to detect prion seeding activity compared with the cerebrospinal fluid (CSF) as a diagnostic biomarker in prion diseases.

Images in Neurology

Crossed Clonus Response

Abstract Full Text
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JAMA Neurol. Published online October 14, 2024. doi:10.1001/jamaneurol.2024.3488

This case report describes a novel crossed clonus response in a 48-year-old man with compressive cervical myelopathy.

October 7, 2024
Viewpoint

Barriers to Tofersen Therapy for Variant SOD1-Mediated ALS

Abstract Full Text
JAMA Neurol. Published online October 7, 2024. doi:10.1001/jamaneurol.2024.3331

This Viewpoint advocates for the accelerated adoption of tofersen therapy to treat patients with variant SOD1-mediated amyotrophic lateral sclerosis (ALS) and describes the current barriers to treatment.

Original Investigation

Directly Isolated Allogeneic Virus–Specific T Cells in Progressive Multifocal Leukoencephalopathy

Abstract Full Text
open access
JAMA Neurol. Published online October 7, 2024. doi:10.1001/jamaneurol.2024.3324

This case series investigates if directly isolated allogenic virus–specific T cells are associated with a therapeutic outcome in patients with progressive multifocal leukoencephalopathy (PML).

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